news
Publication – Hoop et al (2014) “Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state NMR.”
New publication on the structure and dynamics in fibrils formed from mutant huntingtin fragments, including a 44-Q exon-1. In the journal Biochemistry: Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state NMR. DOI:http://dx.doi.org/10.1021/bi501010q
Publication – D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells.
New publication on the surprising features of D-polyQ, in the Journal of Molecular Biology: D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells. DOI:http://dx.doi.org/10.1016/j.jmb.2013.11.019
Eastern Analytical Symposium Award – Nov 2013
EAS New Faculty Award in NMR Spectroscopy !
Nov. 19 at the Eastern Analytical Symposium 2013, in Somerset, NJ.
Registration extended: upcoming continuing education tour of the structural biology dept facilities
Event on Oct 12th. Registration deadline: Oct 8th. Organized by the Spectroscopy Society of Pittsburgh:
http://www.ssp-pgh.org/wp-content/uploads/2013/09/SSP-Flyer-Structural-Biology-Tour_2.pdf
Publication – Spinning-rate encoded chemical shift correlations from rotational resonance solid-state NMR experiments
Jun Li’s work on rotational resonance width experiments is published in JMR:
Li, J., & van der Wel, P.C.A. Spinning-rate encoded chemical shift correlations from rotational resonance solid-state NMR experiments. Journal of Magnetic Resonance. 2013;230:117-124. http://dx.doi.org/10.1016/j.jmr.2013.02.004
Publication – β-hairpin-mediated nucleation of polyglutamine amyloid formation
Cody’s collaborative work with the Wetzel group on the structure and formation mechanism of polyglutamine aggregates is published in JMB:
Kar, K., Hoop, C.L., Drombosky, K.W., Baker, M.A., Kodali, R., Arduini, I., van der Wel, P.C.A., Horne, W.S., & Wetzel, R. β-hairpin-mediated nucleation of polyglutamine amyloid formation. J Mol Biol. 2013;425(7):1-45.
MBSB T32 fellowship awarded to Cody!
The Pitt/CMU Molecular Biophysics & Structural Biology graduate program has awarded one of its three T32 fellowships to Cody. Congratulations and great job!
New website
New wordpress-based website is now (more or less) functional.