Tag: inhibitors
Publication: Impact of aggregation inhibitors on protein aggregation and aggregate toxicity.
Congratulations to Greeshma Jain, Marina Trombetta-Lima and the whole team of co-authors for the publication of our most recent paper on Huntington’s disease (HD), in the journal Nature Communications. This paper is actually the fourteenth peer-reviewed publication from the lab on HD research, since our first paper in 2011. It was enabled by crucial funding from the CampagneTeam Huntington foundation, who supported our HD research program when the Van der Wel group moved back to the Netherlands. In this new report we describe our use of structural analysis (NMR and EM) to look how aggregation-inhibiting small molecules (polyphenols) change the […]