conference
Educational webinar on the use of ssNMR to measure dihedral angles.
Recently, Patrick gave an online lecture in the online webinar tutorial series of the Global NMR Discussion Meetings series (episode 70!). In this online lecture he introduced and discussed approaches to measure torsion angles (or dihedral angles) using advanced solid-state NMR spectroscopy. He discussed the basic idea of how these are implemented in ssNMR, but also how such structural data can be a useful complement to more traditional inter-atomic distance information obtained by ssNMR. You can now watch the recording of this lecture on Youtube, via this link. Want to learn even more? This lecture is connected to our recent […]
Upcoming event: BPS networking event on polyQ biophysics
Hereby an early announcement of an upcoming online event hosted by our group and the group of Markus Miettinen: “Biophysics of polyglutamine aggregation: how does it start and how does it end?“ This is an online event is organized in context of the networking event series sponsored and organized by the Biophysical Society (BPS). Our event aims to bring together international scientists working on the biophysics of polyglutamine (polyQ) protein aggregation. The event will take place on July 6th 2022, from 15:00-18:00 CET. More information can be found at the page from the BPS or our own institute. An online […]
Webinar: Huntington’s disease mechanisms.
On Sept 28 2021, Patrick gave a public webinar on the topic of protein Misfolding and aggregation in Huntington’s disease (and related polyglutamine disorders). This was part of the international webinar series on Cellular and Protein Homeostasis. This webinar is now available for streaming online at the following URL (updated URL in 2024). The webinar discusses some of the lessons we learned from our ongoing studies of what happens to mutated proteins in Huntington’s disease. In particular: what is the role of the mutated polyglutamine domain? How does it change its conformation as it transitions from its normal fold to […]
Webinar: Structural biology of Huntington’s disease.
On May 15th 2021, Patrick gave an invited lecture in the online webinar series on the Molecular Bases of Proteinopathies hosted by the Ramamoorthy lab at the University of Michigan. Patrick talked about our research on polyglutamine protein aggregation and the structural biology of Huntington’s disease.The seminar title was “The Structural Biology of Protein Misfolding in Huntington’s disease”. If you are interested, the seminar has been posted to YouTube, where it can be viewed here.
Webinar: Talk on dynamics ssNMR studies in the Emerging Topics in Biomolecular Magnetic Resonance series
On Thu Feb 18th, Patrick was invited to give a talk in the online Emerging Topics in Biomolecular Magnetic Resonance webinar series. This is a global online seminar series featuring the frontier of research using magnetic resonance spectroscopy (mostly NMR) in biological systems. The webinars are also posted (most of them at least) to the dedicated YouTube channel. Lots of great cutting edge research there! Patrick presented a combination of published an unpublished research that focused on the studies of how lipid (per)oxidation is catalysed in mitochondria, as part of the mitochondrial apoptotic process. Whilst oxidation of biomolecules (lipids, DNA, […]
Online presentation: our work featured in the Polymer Physics & Polymer Spectroscopy (P3S) webinar series
Patrick was invited to present some of our work in the P3S webinar series organised by three research groups from Europe, China and the US. This recurring series has included many interesting talks on studies of polymers and hydrogels by various spectroscopic techniques, with a recurring role for (solid-state) NMR spectroscopy. Patrick spoke about our published work on studying the repeating polymer structures of polyglutamine proteins [1] and (briefly) our newer investigations of polysaccharide hydrogels [2] . In the former topic, the talk discussed the use and benefits of torsion angle measurements by solid-state NMR, as demonstrated in our prior […]
Webinars of interest (during COVID)
During the COVID19 pandemic many conferences were cancelled, but also various interesting new online alternatives came into being. Below are a few relevant seminar series with relevance to our past and current research. Protein aggregation & chaperones Proteostasis Consortium Protein Society Webinars Protein Folding and Dynamics IDP seminars IDP SIG Molecular Bases of Proteinopathies NMR related Emerging Topics in Biomolecular Magnetic Resonance (YouTube) Global NMR Discussion meetings (YouTube) MIT SSNMR/DNP zoom seminars P3S seminars MLU Halle ICMRBS Early Careers Seminars Intercontinental NMR Seminar Series (ICONS2020) Membranes and lipids ASBMB Lipid Research Division seminars Biophysics KNAW BiophysicsNL Talks
Van der Wel lab at the Biophysical Society Meeting in San Francisco!
This coming week the Van der Wel lab will be represented at the annual meeting of the Biophysical Society, taking place in San Francisco. As summarized below, a recurring theme in the presented work will be the impact of oxidative damage in health and disease. Dr. Mingyue Li will present her studies of mitochondrial protein-lipid interactions during her platform session talk on Monday Feb. 19 (1130AM; 999-PLAT). She will talk about the structure and dynamics of the cardiolipin-cytochrome c complex that is implicated in the early stages of mitochondrial apoptosis. This protein/lipid complex features a peripherally bound protein that facilitates […]
ENC NMR conference coming to Pittsburgh
This coming spring the Experimental NMR Conference (ENC) is returning to Pittsburgh. The ENC poster, including a list of invited speakers, is available here. To submit your abstract, go to this page by Jan 8th 2016 (which is the abstract deadline). The registration deadline is March 18th 2016. Dates: April 10-15, 2016 Location: Wyndham Grand Pittsburgh Downtown Program: ENC website
Biophysical Society meeting news!
Congratulations to Jennifer and Abhishek, for being selected for a talk and awarded travel grants for the coming Biophysical Society Meeting in San Diego! We look forward to seeing you there, and tell you more about our studies of protein deposition diseases and protein-lipid interactions. Update: see also the press release by the Biophysical Society.